The drug of the Applied Research Center includes 14 laboratories equipped in various fields of pharmaceutical sciences and related fields that can provide you with the following brief descriptions:
Pharmacognosy Laboratory
Providing services that can be provided:
1- Extraction and fractionation of different plant extracts
2- Essential oil extraction from aromatic plants
3- Qualitative and initial identification of different groups of natural compounds by chemical and instrumental methods
4- Isolation and determination of amount of medical and industrial compounds by different chromatographic methods such as TLC, GC and HPLC (analytical and preliminary)
5- Determining the chemical structure of natural and industrial composition by selecting HNMR, 13CNMR and cozy
6- Usually plant extracts for use in medicinal processes
7- Determining the antioxidant activity of extracts, fractions and pure compounds
8- Determining the general toxicity of different compounds
9- Sample analysis by GC-MS
10- Scientific consultation with production and research units
Pharmacology Laboratory
Providing services that can be provided:
1- Homogenization of tissues and cellular, plant, animal, organic and inorganic materials by two homogenizers with different cycles of 1500-35000 and
1500-150 rpm.
2- Record of blood pressure (Invasive-Noninvasive), vascular contractions, cardiovascular parameters by Powerlab.
3- Registration of cardiac parameters and ECG along with change in body temperature by telemetry
4- Evaluation of analgesic effect of different compounds in animals and reactions performed by Hot Plate device and formalin test.
Evaluation of morphine tolerance and dependence
6- Stereotaxic device
Laboratory of histology and cell biology
Providing services that can be provided:
1- Preparation of all biological and non-biological samples
2- Preparation of semi-thin and thin sections from biological and non-biological samples
3- Photographing biological and non-biological samples
4- Cooperation with the pathology department of hospitals
Radiopharmacy Laboratory
Providing services that can be provided:
1. Perform tests that require ELISA in their system, such as hormones
2. Perform tests that require a liquid centrifuge, such as hormones.
Physiology Laboratory
Providing services that can be provided:
1- Electric kindling (epilepsy model) in laboratory animals
2- Magnetic field generating device: to study the effect of magnetic field on laboratory animals
3- Investigating the effects of exercise on various parameters by the Treadmill device
4- Animal brain surgery by stereotex device
5- Investigation of the effect of intracerebral injection of different herbal compounds on learning and memory
6- Investigating the effects of intracerebral injection of new traditional drug compounds in learning and memory, including avoidance memory (box shuttle) and
Spatial memory (Mauritius Mauritius water)
7- Recording of blood pressure (Invasive-Noninvasive), vascular contractions, cardiovascular parameters by Powerlab.
Bacteriological laboratory
Providing services that can be provided:
1- Molecular and cellular studies of microorganisms
2- Investigation of pathogenesis and microbial diseases
3- Study of gene expression and cellular change of microbes
4- Isolation of local samples and probiotic microbes
5- Investigation of antibiotic resistance mechanisms
6- Phylogenetic studies on microbes
7- Microbial bank in East Azerbaijan region
8- Bioinformatics studies on microbes
9- Determination of microbial identity
10. Evaluation affects the microbial environment
Animal Lab
Providing services that can be provided:
1- Performing various surgeries on laboratory animals
2- Applying different diets on laboratory animals
Formulation laboratory
Providing services that can be provided:
1- Control of drug formulations
2- Optimization of formulations
3- New formulations to the pharmaceutical industry of the private country in the fields of dermatology and inhalation
4- Scientific consultation with research and industrial centers
Synthesis laboratory
Providing services that can be provided:
1- Identification, isolation and precise determination of molecular mass of organic and pharmaceutical compounds (LC / MS)
2- Determination of melting point and glass transition point using differential scanning heating (DSC)
2. Determine the elements carbon, hydrogen, nitrogen, sulfur and oxygen using the device (CHNSO)
3- Detection and identification of different types of chemicals by the device (FTIR)
4 - Detection and identification of compounds and their quantitative analysis (HPLC)
5 - Drying the compounds using the summary oven
General laboratory
Providing services that can be provided:
1- Measurement of biochemical parameters such as glucose, urea, creatinine, uric acid, cholesterol, ether glyceride, HD iodine, LDL, VLDL, AST, ALT, ALP, etc. by auto-analyzer
2- Storing different samples in the freezer with a temperature of 70-
3- Specialized enzyme tests such as superoxide dismutase, total antioxidant, glutathione peroxidase, etc.
4- Measurement and evaluation of parameters related to heart diseases such as: CRP, Lpa, APO A, etc.
5 - Tests such as urea, creatinine, uric acid, calcium and phosphorus in blood and urine, urinary microalbumin, blood albumin and ...
6- Measurement of hormones and some substances by the technique of cumoluminas.
Laboratory of Food Science and Medicinal Foods
Providing services that can be provided:
1- Analysis of food in terms of nutrients, contaminants, additives, etc.
2- Analysis, extraction and purification of Nutraceuticals
3- Isolation and identification of substances and drugs in biological fluids and pharmaceutical and food formulations as types of definition of type and amount of acid has different preparations.
In food
4 - Measuring the caloric content of food
Immunology Laboratory
Providing services that can be provided:
1- Performing various types of electrophoresis horizontally and vertically, isoelectric focus (IEF), two-dimensional electrophoresis (two-dimensional gel electrophoresis) and immunoelectrophoresis
Western blot
3- Production of various antiMonoclonal and polyclonal bodies
3- Labeling different types of antibodies with peroxidase enzyme
4- Purification of proteins by ion exchange and affinity chromatography
5- Performing various immunological tests based on ELISA and immunofluorescence
6- Concentration and lyophilization of various biological and chemical solutions
7- Cell culture
8- Measurement of cytokines
Drug Analysis Laboratory
Services available:
1- Measurement of drugs in biological fluids and drug formulations by HPLC and GC methods
2- Measurement of metals by atomic absorption device
3- Measurement of fluorescent material by spectrofluorimeter
4- Performing all spectrophotometric measurements
5- Measuring samples using Auto Lab electrochemical device
Drug and Chemistry Design Laboratory
Services available:
Providing scientific advice and performing the necessary calculations in the fields of molecular modeling, chemometry and quantitative structure interface (QSAR) These techniques can be used to predict the extent and mechanism of various biological processes such as (adsorption, diffusion, metabolism, Disposal, toxicity of drugs), drug effect, presentation of mathematical and statistical models to model the physicochemical properties required in the pharmaceutical and chemical industries such as solubility, chromatographic properties, release, wettability, etc. to be used in addition to cost reduction studies And drug development is one of the essential pillars in these processes.
Toxicology laboratory
Services available:
1- Investigation of toxicity of natural and chemical substances at cellular and molecular level
2- Evaluation of cell damage caused by various factors such as radiation and oxidative stress
3- Investigation of protective effects of drugs and substances of natural and plant origin against damage caused by various factors
4- Therapentic Drug Monitoring
5 - Detection and cloning of genes involved in the metabolism of drugs and various substances in cancer cells
6- Study of polymorphism of genes of enzymes involved in metabolism of drugs and toxins
7- Laboratory diagnosis of substance poisoning
8- Measurement of trace elements in samples of animal and human origin
9- Investigating contact with hazardous chemicals such as arsenic for occupational and environmental reasons and their detection in food and drinking water
10 - Screening of drugs and compounds that are abused.
11- Imaging of biological samples by fluorescence microscope
Central Laboratory
Services available:
1- Measurement of particle size and zeta potential using dynamic light scattering device (DLS)
2- Preparation of nanofibers using electrospinning device